Searchable abstracts of presentations at key conferences in endocrinology

ea0041gp195 | Thyroid - Basic | ECE2016

Accumulation of PD-1-positve and PD-L1-positve T and B lymphocytes in patients with Graves’ disease

Pyzik Aleksandra , Grywalska Ewelina , Matyjaszek-Matuszek Beata , Kiszczak-Bochynska Ewa , Rolinski Jacek

Introduction: Programmed death-1 (PD-1) is one of the most important inhibitory co-receptors. Studies show that the PD-1/PD-L1 pathway regulates the induction and maintenance of peripheral tolerance and protects tissues from autoimmune attack in physiological conditions. Several studies have shown association of PD-1/PD-L1 pathway with several autoimmune diseases although, to date, no such studies have been performed for GravesÂ’ disease (GD).Aims: T...